In this lab, we apply physical techniques to study biological interactions. While our primary approach is Optical Tweezers, we apply a variety of techniques, including Tethered Particle Motion, Flow-Forces, Magnetic Tweezers, and Single-Molecule Fluorescence. Despite focusing heavily on instrumentation, our primarily goal is to measure and understand the underlying biological mechanisms. Currently, we are studying the DNA-protein interactions in DNA condensation and V(D)J recombination. Another research area that we focus on is investigating soft condensed matter phenomena via XPCS (X-ray Photon Correlation Spectroscopy). This is located in Argonne National Laboratory.
